Melatonin Stimulates the Release of Gonadotropin-Inhibitory Hormone by the Avian Hypothalamus

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Melatonin induces the expression of gonadotropin-inhibitory hormone in the avian brain.

We recently identified a novel hypothalamic neuropeptide inhibiting gonadotropin release in quail and termed it gonadotropin-inhibitory hormone (GnIH). Cell bodies and terminals containing the dodecapeptide GnIH are localized in the paraventricular nucleus (PVN) and median eminence, respectively. To understand the physiological role of GnIH, we investigated the mechanisms that regulate GnIH exp...

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effect of lactation on the expression of gonadotropin-inhibitory hormone in dorsomedial and paraventricular nuclei of the rat hypothalamus

introduction: gonadotropin inhibitory hormone (gnih) is believed to be an inhibitor of gonadotropin releasing hormone (gnrh) secretion. the role of gnih in lactational inhibition of gonadotropin secretion is not well known therefore, the aim of the present study was to evaluate the effect of lactation on expression of gnih in these nuclei of lactating and non-lactating rats. methods: ten postpa...

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ژورنال

عنوان ژورنال: Endocrinology

سال: 2010

ISSN: 0013-7227,1945-7170

DOI: 10.1210/en.2009-0908